| Week | Date | Opponent | Time (ET) |
|---|---|---|---|
| 1 | September 13 | at Browns | 1:00 PM ET |
| 2 | September 20 | Chargers | 4:05 PM ET |
| 3 | September 27 | at Chiefs | 1:00 PM ET |
| 4 | October 4 | Dolphins | 1:00 PM ET |
| 5 | October 11 | at Chargers | 4:05 PM ET |
| 6 | October 18 | Bye | |
| 7 | October 25 | at Saints | 1:00 PM ET |
| 8 | November 1 | Bills | 1:00 PM ET |
| 9 | November 8 | at 49ers | 4:05 PM ET |
| 10 | November 15 | Titans | 1:00 PM ET |
| 11 | November 22 | at Jets | 1:00 PM ET |
| 12 | November 29 | Rams | 4:25 PM ET |
| 13 | December 6 | Chiefs | 4:05 PM ET |
| 14 | December 13 | at Cardinals | 4:05 PM ET |
| 15 | December 20 | at Broncos | 4:05 PM ET |
| 16 | December 27 | Seahawks | 4:05 PM ET |
| 17 | January 3 | at Patriots | 1:00 PM ET |
| 18 | January 10 | Broncos | TBD (Flex Scheduling - Nighttime) |