| 1 |
September 10 |
49ers |
8:35 PM ET (Thursday Night Football in Melbourne) |
| 2 |
September 21 |
at Commanders |
8:15 PM ET (Monday Night Football) |
| 3 |
September 27 |
Giants |
4:05 PM ET |
| 4 |
October 4 |
at Cardinals |
4:05 PM ET |
| 5 |
October 11 |
Bye |
| 6 |
October 18 |
Packers |
4:25 PM ET |
| 7 |
October 25 |
Chiefs |
4:05 PM ET |
| 8 |
November 1 |
at Eagles |
4:25 PM ET |
| 9 |
November 8 |
at Broncos |
8:20 PM ET (Sunday Night Football) |
| 10 |
November 15 |
Seahawks |
4:25 PM ET |
| 11 |
November 19 |
Chargers |
8:15 PM ET (Thursday Night Football) |
| 12 |
November 29 |
at Raiders |
4:25 PM ET |
| 13 |
December 6 |
at Buccaneers |
1:00 PM ET |
| 14 |
December 13 |
Bills |
4:25 PM ET |
| 15 |
December 20 |
at Seahawks |
8:20 PM ET (Sunday Night Football) |
| 16 |
December 27 |
Cardinals |
4:05 PM ET |
| 17 |
January 3 |
Cowboys |
4:25 PM ET |
| 18 |
January 10 |
at 49ers |
TBD (Flex Scheduling - Nighttime) |